The impact of prothrombin complex concentrates when treating DOAC-associated bleeding: a review
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چکیده
منابع مشابه
Prothrombin complex concentrates: a brief review.
Prothrombin complex concentrates are haemostatic blood products containing four vitamin K-dependent clotting factors (II, VII, IX and X). They are a useful, reliable and fast alternative to fresh frozen plasma for the reversal of the effects of oral anticoagulant treatments (vitamin K antagonists). They are sometimes used for factor II or factor X replacement in patients with congenital or acqu...
متن کاملProthrombin Complex Concentrates for Bleeding in the Perioperative Setting.
Prothrombin complex concentrates (PCCs) contain vitamin K-dependent clotting factors (II, VII, IX, and X) and are marketed as 3 or 4 factor-PCC formulations depending on the concentrations of factor VII. PCCs rapidly restore deficient coagulation factor concentrations to achieve hemostasis, but like with all procoagulants, the effect is balanced against thromboembolic risk. The latter is depend...
متن کاملProthrombin complex concentrates in trauma and perioperative bleeding.
923 April 2015 P rothrombin complex concentrates (PCCs) are recommended in preference to other treatments such as therapeutic plasma for urgent reversal of vitamin K antagonists.1,2 PCCs contain either three or four coagulation factors (factors ii, iX, and X, with or without factor Vii) and, depending on formulation, low doses of coagulation inhibitors such as protein C, protein S, and heparin ...
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امروزه تصحیح همکلاسی در کلاسهای نگارش یکی از اجزاء لاینفک کلاسهای دانش آموز محور است. تاثیرات مفید تصحیح همکلاسی بر زبان آموزان، معلمان را متقاعد کرده است که علیرغم صرف زمان، انرژی و توان بسیار، از این شیوه ی آموزشی در کلاسهای آموزش نگارش بهره بگیرند. تحقیق حاضر بر آن است تا با مقایسه دو گروه از یادگیرندگان زبان انگلیسی، تاثیر تصحیح همکلاسی را بر توانایی نوشتاری آنها نشان دهد. 122 خانم زبان آمو...
15 صفحه اولClinical review: Prothrombin complex concentrates - evaluation of safety and thrombogenicity
Prothrombin complex concentrates (PCCs) are used mainly for emergency reversal of vitamin K antagonist therapy. Historically, the major drawback with PCCs has been the risk of thrombotic complications. The aims of the present review are to examine thrombotic complications reported with PCCs, and to compare the safety of PCCs with human fresh frozen plasma. The risk of thrombotic complications m...
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ژورنال
عنوان ژورنال: International Journal of Emergency Medicine
سال: 2018
ISSN: 1865-1372,1865-1380
DOI: 10.1186/s12245-018-0215-6